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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK3
All Species:
8.48
Human Site:
Y298
Identified Species:
11.67
UniProt:
Q00526
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00526
NP_001249.1
305
35046
Y298
P
S
P
A
A
R
Q
Y
V
L
Q
R
F
R
H
Chimpanzee
Pan troglodytes
XP_523720
325
36841
Y318
P
S
P
A
A
R
Q
Y
V
L
Q
R
F
H
H
Rhesus Macaque
Macaca mulatta
XP_001102596
305
34903
Y298
P
S
P
A
A
R
Q
Y
V
L
Q
R
F
C
R
Dog
Lupus familis
XP_540442
303
34173
C296
T
S
P
A
P
H
Q
C
V
L
E
R
F
C
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80YP0
303
33870
Rat
Rattus norvegicus
Q63699
298
33869
T290
H
P
F
F
Q
D
V
T
K
P
V
P
H
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
Frog
Xenopus laevis
P23437
297
33852
S290
H
P
F
F
R
D
V
S
R
P
T
P
H
L
I
Zebra Danio
Brachydanio rerio
NP_998571
298
34001
T290
H
R
F
F
R
D
V
T
M
P
V
P
P
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
F290
E
H
P
Y
F
N
G
F
Q
S
G
L
V
R
N
Honey Bee
Apis mellifera
XP_393450
299
34033
P292
F
N
G
V
T
L
V
P
P
P
L
P
K
K
T
Nematode Worm
Caenorhab. elegans
P34556
332
38277
N324
T
S
K
L
P
A
G
N
Y
R
G
E
L
E
L
Sea Urchin
Strong. purpuratus
XP_790847
299
34142
K290
H
P
Y
F
K
D
V
K
M
V
P
P
P
R
L
Poplar Tree
Populus trichocarpa
XP_002306004
294
33768
H284
T
A
R
S
A
L
E
H
E
Y
F
K
D
I
G
Maize
Zea mays
P23111
294
33816
H284
T
A
R
Q
A
L
E
H
E
Y
F
K
D
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
H284
N
A
R
A
A
L
E
H
E
Y
F
K
D
L
G
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
96.7
88.5
N.A.
82.6
74.7
N.A.
N.A.
63.6
73.7
73.7
N.A.
62.9
67.2
58.1
69.5
Protein Similarity:
100
93.5
98.3
92.7
N.A.
91.8
84.5
N.A.
N.A.
78
84.5
83.2
N.A.
76.7
80.6
69.5
82.6
P-Site Identity:
100
93.3
86.6
53.3
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
13.3
0
6.6
6.6
P-Site Similarity:
100
93.3
86.6
60
N.A.
0
0
N.A.
N.A.
0
0
6.6
N.A.
26.6
13.3
6.6
20
Percent
Protein Identity:
65.2
64.2
N.A.
65.5
62.3
N.A.
Protein Similarity:
81.6
80.9
N.A.
81.3
77.7
N.A.
P-Site Identity:
6.6
6.6
N.A.
13.3
0
N.A.
P-Site Similarity:
40
33.3
N.A.
40
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
18
0
30
36
6
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
6
0
0
0
0
0
12
0
% C
% Asp:
0
0
0
0
0
24
0
0
0
0
0
0
18
0
0
% D
% Glu:
6
0
0
0
0
0
18
0
18
0
6
6
0
6
6
% E
% Phe:
6
0
18
24
6
0
0
6
0
0
18
0
24
0
0
% F
% Gly:
0
0
6
0
0
0
12
0
0
0
12
0
0
0
12
% G
% His:
24
6
0
0
0
6
0
18
0
0
0
0
12
6
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
6
% I
% Lys:
0
0
6
0
6
0
0
6
6
0
0
18
6
6
0
% K
% Leu:
0
0
0
6
0
24
0
0
0
24
6
6
6
30
12
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
6
6
0
0
0
6
0
6
0
0
0
0
0
0
6
% N
% Pro:
18
18
30
0
12
0
0
6
6
24
6
30
12
0
0
% P
% Gln:
0
0
0
6
6
0
24
0
6
0
18
0
0
0
0
% Q
% Arg:
0
6
18
0
12
18
0
0
6
6
0
24
0
18
24
% R
% Ser:
0
30
0
6
0
0
0
6
0
6
0
0
0
0
0
% S
% Thr:
24
0
0
0
6
0
0
12
0
0
6
0
0
0
6
% T
% Val:
0
0
0
6
0
0
30
0
24
6
12
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
6
0
0
0
18
6
18
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _